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Recently, Louisville has came about as a major gathering place for the health care and professional medical sciences market sectors. Louisville has been key to progress in heart and hand surgery treatment as well as cancer medication. A few of the first manufactured coronary heart transplants were made in Louisville. Louisville's flourishing downtown medical research grounds contains a brand new $88 thousand rehab community, and a health and wellbeing sciences investigation and commercialization park that, in partnership with the University of Louisville, has lured nearly 80 top researchers and scientists. Louisville is also home to Humana, one of the nation's greatest health insurance policy businesses.

Louisville is residence to a number of major companies and establishments.